Nassau County police said the victim, whose name was not immediately released, was driving her Mercury Sable southbound on Guinea Woods Road when her car crossed into the northbound lane near the corner of Willets Road and collided with a Freightliner trackor-trailer driven by a 35-year-old man from Mon Junction, New Jersey, at 12:16 a.m.
The woman was pronounced dead at the scene. The truck driver was taken to a local hospital for observation. Both vehicles were impounded for safety checks. There does not appear to be any criminality at this time, according to Third Squad detectives.